Prof. Xiaohua Lei, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China
Dr. Xiaohua Lei is a Professor at the Institutes of Shenzhen Advanced Technology, Chinese Academy of Sciences (CAS), and a prominent member of the Chinese Space Life Professional Committee as well as a workgroup of the China National Standardization Technical Committee in Space Science and Utilization. He holds a Ph.D. in Physiology from China Agricultural University. Dr. Lei was selected as a CAS Key Technology Talent in 2018 and was honored as one of the young space scientists by the National Space Science Center of the Chinese Academy of Sciences and the Space Studies Board of the U.S. National Academies of Sciences, Engineering, and Medicine, participating in the 2016-17 Forum for New Leaders in Space Science. His research interests primarily focus on space life science, particularly exploring how space environments affect stem cell proliferation and differentiation. Dr. Lei has published over 50 peer-reviewed articles in renowned journals, such as National Science Review, Protein & Cell, Cell Proliferation, Nature Communications, and others. He has also earned several academic awards and holds multiple invention patents. His lab aims to advance our understanding of early mammalian development under microgravity, radiation, and hypomagnetic fields, utilizing human or mouse stem cells, mouse embryos, and transgenic mouse models.
Professional Profile:
ORCID
Summary of Suitability for Best Researcher Award: Dr. Xiaohua Lei
Dr. Xiaohua Lei is a highly accomplished researcher and an exemplary candidate for the Best Researcher Award due to his substantial contributions to Space Life Science and his innovative work on understanding the effects of space environments on biological systems. His research on stem cell proliferation, differentiation, and early mammalian development under extreme space conditions, including microgravity, radiation, and hypomagnetic fields, has made significant strides in the field.
Education:
Work Experience:
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Professor, Institutes of Shenzhen Advanced Technology, Chinese Academy of Sciences (CAS) 👨🏫
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Member, Chinese Space Life Professional Committee 🌌
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Member, Workgroup of China National Standardization Technical Committee in Space Science and Utilization 🚀
Achievements:
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Published over 50 peer-reviewed articles in prestigious journals, including National Science Review, Protein & Cell, Cell Proliferation, Nature Communications, and more 📚
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Invention patents in the field of space life science 🛠️
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Research Focus: The effects of space environments on stem cell proliferation and differentiation, and early mammalian development under conditions like microgravity, radiation, and hypomagnetic fields 🔬
Awards & Honors:
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CAS Key Technology Talent (2018) 🏆
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Selected as one of the Young Space Scientists by the National Space Science Center (CAS) and Space Studies Board of U.S. National Academies 🌠
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Forum for New Leaders in Space Science (2016-17) participant 🎖️
Publication Top Notes:
Oxidative Damage Under Microgravity Conditions: Response Mechanisms, Monitoring Methods and Countermeasures on Somatic and Germ Cells
mTOR hypoactivity leads to trophectoderm cell failure by enhancing lysosomal activation and disrupting the cytoskeleton in preimplantation embryo
Stem Cells and Exosome Applications for Cutaneous Wound Healing: From Ground to Microgravity Environment
Melatonin ameliorates simulated‐microgravity‐induced mitochondrial dysfunction and lipid metabolism dysregulation in hepatocytes
Radiotherapy Side Effects: Comprehensive Proteomic Study Unraveled Neural Stem Cell Degenerative Differentiation upon Ionizing Radiation
Synthetic Extracellular Matrices for 3D Culture of Schwann Cells, Hepatocytes, and HUVECs
An Antagonistic Peptide of Gpr1 Ameliorates LPS-Induced Depression through the Hypothalamic-Pituitary-Ovarian Axis
The Determinant of DNA Repair Pathway Choices in Ionising Radiation‐Induced DNA Double‐Strand Breaks