Prof. Xiaohua Lei | Oxidative Damage | Best Researcher Award

Prof. Xiaohua Lei | Oxidative Damage | Best Researcher Award

Prof. Xiaohua Lei, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China

Dr. Xiaohua Lei is a Professor at the Institutes of Shenzhen Advanced Technology, Chinese Academy of Sciences (CAS), and a prominent member of the Chinese Space Life Professional Committee as well as a workgroup of the China National Standardization Technical Committee in Space Science and Utilization. He holds a Ph.D. in Physiology from China Agricultural University. Dr. Lei was selected as a CAS Key Technology Talent in 2018 and was honored as one of the young space scientists by the National Space Science Center of the Chinese Academy of Sciences and the Space Studies Board of the U.S. National Academies of Sciences, Engineering, and Medicine, participating in the 2016-17 Forum for New Leaders in Space Science. His research interests primarily focus on space life science, particularly exploring how space environments affect stem cell proliferation and differentiation. Dr. Lei has published over 50 peer-reviewed articles in renowned journals, such as National Science Review, Protein & Cell, Cell Proliferation, Nature Communications, and others. He has also earned several academic awards and holds multiple invention patents. His lab aims to advance our understanding of early mammalian development under microgravity, radiation, and hypomagnetic fields, utilizing human or mouse stem cells, mouse embryos, and transgenic mouse models.

Professional Profile:

ORCID

Summary of Suitability for Best Researcher Award: Dr. Xiaohua Lei

Dr. Xiaohua Lei is a highly accomplished researcher and an exemplary candidate for the Best Researcher Award due to his substantial contributions to Space Life Science and his innovative work on understanding the effects of space environments on biological systems. His research on stem cell proliferation, differentiation, and early mammalian development under extreme space conditions, including microgravity, radiation, and hypomagnetic fields, has made significant strides in the field.

Education:

  • Ph.D. in Physiology, China Agricultural University 🎓

Work Experience:

  • Professor, Institutes of Shenzhen Advanced Technology, Chinese Academy of Sciences (CAS) 👨‍🏫

  • Member, Chinese Space Life Professional Committee 🌌

  • Member, Workgroup of China National Standardization Technical Committee in Space Science and Utilization 🚀

Achievements:

  • Published over 50 peer-reviewed articles in prestigious journals, including National Science Review, Protein & Cell, Cell Proliferation, Nature Communications, and more 📚

  • Invention patents in the field of space life science 🛠️

  • Research Focus: The effects of space environments on stem cell proliferation and differentiation, and early mammalian development under conditions like microgravity, radiation, and hypomagnetic fields 🔬

Awards & Honors:

  • CAS Key Technology Talent (2018) 🏆

  • Selected as one of the Young Space Scientists by the National Space Science Center (CAS) and Space Studies Board of U.S. National Academies 🌠

  • Forum for New Leaders in Space Science (2016-17) participant 🎖️

Publication Top Notes:

Oxidative Damage Under Microgravity Conditions: Response Mechanisms, Monitoring Methods and Countermeasures on Somatic and Germ Cells

mTOR hypoactivity leads to trophectoderm cell failure by enhancing lysosomal activation and disrupting the cytoskeleton in preimplantation embryo

Stem Cells and Exosome Applications for Cutaneous Wound Healing: From Ground to Microgravity Environment

Melatonin ameliorates simulated‐microgravity‐induced mitochondrial dysfunction and lipid metabolism dysregulation in hepatocytes

Radiotherapy Side Effects: Comprehensive Proteomic Study Unraveled Neural Stem Cell Degenerative Differentiation upon Ionizing Radiation

Synthetic Extracellular Matrices for 3D Culture of Schwann Cells, Hepatocytes, and HUVECs

An Antagonistic Peptide of Gpr1 Ameliorates LPS-Induced Depression through the Hypothalamic-Pituitary-Ovarian Axis

The Determinant of DNA Repair Pathway Choices in Ionising Radiation‐Induced DNA Double‐Strand Breaks

 

 

Nontobeko Mvubu | Molecular Biology Awards | Best Researcher Award

Dr. Nontobeko Mvubu | Molecular Biology Awards | Best Researcher Award 

Dr. Nontobeko Mvubu, University of KwaZulu-Natal, South Africa.

Dr. Nontobeko Eunice Mvubu is a dedicated Senior Lecturer and Researcher at the University of KwaZulu-Natal. With a strong academic background and a PhD in Microbiology (2016), she has been advancing her field through impactful research, particularly focusing on Mycobacterium tuberculosis and bioinformatics. She has over five years of experience in higher education, excelling in teaching and supervising students across multiple levels. Her achievements include supervising 11 Honours, 6 Masters, and 1 PhD student to completion, funded by both national and international grants. Dr. Mvubu has authored 12 publications in Q1 and Q2 journals and contributed significantly to advancing understanding in her field through innovative research and academic excellence. 🌍📚

Professional Profile

Google Scholar

Researcher Suitability Summary for Best Researcher Award

Dr. Nontobeko E. Mvubu’s professional accomplishments and qualifications make her a compelling candidate for the “Best Researcher Award.” Below is an evaluation of her strengths, areas for improvement, and a conclusion regarding her suitability for this prestigious recognition.

Education 🎓

Dr. Mvubu has an extensive academic background:

  • PhD in Microbiology (2013–2016, University of KwaZulu-Natal) – Specialized in molecular and cellular responses to Mycobacterium tuberculosis.
  • MSc in Microbiology (2011–2013, converted to PhD, University of KwaZulu-Natal).
  • BSc Honours in Microbiology (2010, University of KwaZulu-Natal).
  • BMedSc in Physiology (2007–2009, University of KwaZulu-Natal).
  • Matric (2006, Impoqabulungu Secondary).
    Her academic foundation combines rigorous training with a focus on microbiology and physiology, paving the way for her groundbreaking research. 📖🧬

Experience 💼

Dr. Mvubu began her academic journey as a Lecturer in 2017, rising to Senior Lecturer in 2023. She has taught undergraduate modules in genetics, microbiology, and physiology, with courses ranging from RDNA202 to advanced topics like MICR701 and MMGY7ALM1. She coordinates modules, develops curricula, and integrates innovative pedagogies in her teaching. Dr. Mvubu also actively mentors graduate and postgraduate students, contributing to their academic success. Her experience extends to being a reviewer for international journals and managing research grants, showcasing her leadership and collaborative skills. 🏫✨

Research Interests 🔬

Dr. Mvubu’s research focuses on Mycobacterium tuberculosis, delving into transcriptomic and epigenetic regulation, strain heterogeneity, and host-pathogen interactions. Her bioinformatics expertise drives studies on inflammasomes, lipid metabolism, and molecular signatures in infectious diseases. She is also exploring novel diagnostic methods and therapeutic strategies using systems biology approaches. Her work bridges microbiology and computational science, contributing to global health solutions. 🌐🧫

Awards 🏆

Dr. Mvubu has received several accolades, including:

  • KRITH Collaborative Grant Award (2011).
  • NRF Thuthuka Funding (Post-PhD Track: 2018, 2021).
  • European and Developing Countries Clinical Trials Partnership Fellowship (2021).
  • South African Medical Research Council (MRC) Grant (2022).
    These awards recognize her innovative research and commitment to tackling health challenges in infectious diseases. 🌟💡

Publications Top Notes 📜

Dr. Mvubu’s impactful publications include:

Canonical pathways, networks and transcriptional factor regulation by clinical strains of Mycobacterium tuberculosis in pulmonary alveolar epithelial cells

CITED: 37

Mycobacterium tuberculosis strains induce strain-specific cytokine and chemokine response in pulmonary epithelial cells

CITED: 31

Lineage-specific differences in lipid metabolism and its impact on clinical strains of Mycobacterium tuberculosis

CITED: 15

Mycobacterium tuberculosis-Induced Maternal Immune Activation Promotes Autism-Like Phenotype in Infected Mice Offspring

CITED: 14

Mycobacterium tuberculosis strains exhibit differential and strain-specific molecular signatures in pulmonary epithelial cells

CITED: 12

Clinical strains of Mycobacterium tuberculosis exhibit differential lipid metabolism-associated transcriptome changes in in vitro cholesterol and

infection models

CITED: 8

Infection of pulmonary epithelial cells by clinical strains of M. tuberculosis induces alternate splicing events

CITED: 7